Short reports Absence of HHV-8 DNA sequences in malignant mesothelioma
نویسندگان
چکیده
Human herpesvirus 8 (HHV-8) associated primary eVusion lymphomas arise and grow in the body cavities as eVusions, but it is not known whether the lining of body cavities and mesothelium derived malignancies are potential targets of HHV-8 infection. We examined a series of 13 diVuse malignant mesotheliomas and four mesothelial cell rich eVusion samples of non-neoplastic aetiology from nonimmunodepressed patients using the polymerase chain reaction to detect HHV-8 specific sequences. HHV-8 amplification products were absent in diVuse malignant mesotheliomas and in nonneoplastic eVusions samples. These results suggest that HHV-8 has a selective tropism among body cavity based tumours, being confined to primary effusion lymphomas. (J Clin Pathol:Mol Pathol 1998;51:113–114)
منابع مشابه
Absence of HHV-8 DNA sequences in malignant mesothelioma.
Human herpesvirus 8 (HHV-8) associated primary effusion lymphomas arise and grow in the body cavities as effusions, but it is not known whether the lining of body cavities and mesothelium derived malignancies are potential targets of HHV-8 infection. We examined a series of 13 diffuse malignant mesotheliomas and four mesothelial cell rich effusion samples of non-neoplastic aetiology from non-im...
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